Borderlands 4 Boss Drops | All Boss Loot & Locations
Farming Legendaries in Borderlands 4 often comes down to bosses. Each boss has its own loot pool, making them the most consistent way to target farm specific items. While random drops can happen anywhere, focusing on bosses greatly increases your odds of scoring the weapons or gear you’re after.
Note: This guide is a W.I.P.
How Boss Drops Work
Bosses have dedicated loot tables that improve your chances at certain Legendaries. Defeating them not only gives a large chunk of loot but also access to repeat farming. Using Moxxi’s Big Encore Machine, you can instantly respawn most bosses for another shot at their drops.
Vault bosses and Rift Challenge bosses also count as farmable, though they hit harder and may take longer.
List of Bosses, Locations, and Drops (Loot)
Below is a full list of known bosses in Borderlands 4 and where to find them.
| Boss | Location | Region | Known Drops |
|---|---|---|---|
| Bio-Bulkhead | Synthetic Nave (Main Mission: One Fell Swoop) | Fadefields | Budget Deity, Sho Kunai, Waterfall |
| Callis, the Ripper Queen | Moon-Called Throne (Main Mission: Her Flaming Vision) | Carcadia Burn | Queen's Rest, Pandoran Memento, Agile Esgrimidor, Professional Skeptic, Prismatic Illusionist, Resounding Viking |
| Callous Harbringer of Annihilating Death | "Craven's Nook" Order Bunker | Terminus Range | Hot Slugger, Kaleidosplode, Atling Gun |
| Driller Hole | Queen's Cradle | Carcadia Burn | Updating Soon |
| Horace | Horace's Oversight (Main Mission: Down and Outbound) | Fadefields | Aegon's Dream, Lucky Clover, Whiskey Foxtrot, Pacemaker, Sho Kunai |
| Idolator Sol | Fortress Indomita (Main Mission: Rush the Gate) | Fadefields | Onslaught, Goremaster, Golden God, Ultimate Bio-Robot, Perpetual Dancer, Excitable Technomancer, Melting Furnace |
| Moon-Maddened Callis | Elpis Orbital Shatterfield | Carcadia Burn | Updating Soon |
| Primordial Guardian Inceptus | Arch of Inceptus (Side Mission: Primordial Vault: Fadefields) | Fadefields | Lucky Clover, Husky Friend, Extra Medium, Ravenfire, Firey Elementalist, Rewarding Filantropo, Electric Avatar |
| Skyspanner Kratch | Unknown | Terminus Range | Updating Soon |
| Sludgemaw | Watershed Gate (Side Mission: All Charged Up) | Fadefields | Birt's Bees, Kickballer, Onion |
| Splashzone | Riptide Grotto (Main Mission: Recruitment Drive) | Fadefields | Lead Balloon, Firewerks, Jelly |
| The Oppressor | The Killing Floors (Main Mission: A Lot to Process) | Fadefields | Asher's Rise, Onslaught, Blood Analyzer, Streamer |
| Timekeeper | Upper Dominion | Dominion | Updating Soon |
| Vile Lictor | Umbral Foundry | Terminus Range | Updating Soon |
| Vile Prototype | Lictor's Black Site | Terminus Range | Updating Soon |
| Warden Scathe | Welcome Center (Main Mission: Guns Blazing) | Fadefields | Lucky Clover, Updating Soon |
Farming Tips
Use Moxxi’s Big Encore Machine to quickly respawn bosses for farming.
Vault bosses drop the most loot and spawn extra red chests, but they are much stronger.
Rift Challenges let you fight random bosses for loot, but you only get one shot per event.
Red chests in boss arenas often respawn after a cooldown—check them between runs.
Always bring elemental variety. Many bosses have resistances or weaknesses tied to their location.
Final Blurb
Borderlands 4 bosses are the most reliable way to farm Legendaries. From early fights like Splashzone to late-game threats like Idolator Sol, each one carries its own loot pool worth grinding.
Use Encore Machines for quick resets, Vaults for high-value fights, and Rift Challenges when they appear.
FAQ
Can all Borderlands 4 bosses be farmed?
Yes, most story and Vault bosses can be respawned using Moxxi’s Big Encore Machine.
Do bosses always drop Legendaries?
No, but each boss has a higher chance to drop certain items from their loot pool.
Are Rift Challenge bosses worth farming?
Yes, Rift bosses can drop high-end loot, though they are random and not tied to a single item.

