Slay The Spire 2 Colorless Cards Tier List

Colorless cards in Slay the Spire 2 can appear through events, shops, relic effects, or special rewards. Since any character can use them, the right pick can quietly carry a run from the first act all the way to the final boss.

Some of these cards fit into almost any deck. Others only shine in certain builds or situations. Knowing which ones consistently provide value makes it much easier to decide when a colorless reward is actually worth grabbing.

Best Colorless Cards In Slay The Spire 2

The best colorless cards in Slay the Spire 2 are Apotheosis, Scrawl, Panache, Master of Strategy, and Hand of Greed because they consistently improve most decks.

These cards offer powerful draw, scaling damage, or long term value that helps in nearly every run. When one of these appears as a reward, it is usually a very safe pick… While this is general advice, obviously your results may vary based on what specific kind of deck you are running and some cards may work better for you than others given the context!

S Tier Colorless Cards Worth Taking

These cards are almost always strong choices.

Apotheosis
Scrawl
Panache
Master of Strategy
Hand of Greed

Apotheosis upgrades every card in your deck for the rest of the combat. That kind of boost can completely change how a fight plays out.

Scrawl and Master of Strategy provide huge card draw which keeps your turns flowing smoothly. Panache rewards decks that play many cards in one turn. Hand of Greed provides solid damage while also generating extra gold during a run.

A Tier Colorless Cards With Strong Utility

These cards are powerful but depend slightly more on your deck.

Discovery
Secret Technique
Secret Weapon
Dark Shackles
Thinking Ahead

Discovery creates flexible options during a turn by offering a random card choice that costs zero that turn. Secret Technique and Secret Weapon allow you to pull important cards directly from your draw pile.

Dark Shackles temporarily removes enemy Strength which can prevent heavy damage. Thinking Ahead lets you control your draw order which becomes very useful during longer fights.

B Tier Colorless Cards That Work In Certain Decks

These cards can become strong when the deck supports them.

Automation
Prep Time
Prowess
Rolling Boulder
Mayhem

Automation rewards decks that draw many cards by generating extra energy. Prep Time grants Vigor each turn which steadily increases attack damage.

Prowess provides both Strength and Dexterity which improves offense and defense at the same time. Rolling Boulder deals scaling damage each turn. Mayhem automatically plays the top card of your deck every turn which can create interesting turns if your deck is built around it.

C Tier Colorless Cards With Niche Uses

These cards can still be useful but depend heavily on the situation.

Mind Blast
The Bomb
Panic Button
Equilibrium
Purity

Mind Blast deals damage based on your draw pile which makes it strongest early in combat. The Bomb deals delayed damage to all enemies after several turns.

Panic Button gives a huge amount of Block but prevents Block cards for the next two turns so timing becomes important. Equilibrium lets you retain your hand. Purity helps remove unwanted cards from your hand during combat.

Colorless Cards That Are Usually Skipped

Some colorless cards rarely outperform normal class cards unless your deck has a very specific plan.

Ultimate Strike
Ultimate Defend
Fasten

Ultimate Strike and Ultimate Defend provide basic damage or block which most decks already handle better. Fasten only improves Defend cards which many players remove from their decks later in a run.

Final Blurb

Colorless cards in Slay the Spire 2 can provide powerful utility, strong draw, or scaling damage. Cards like Apotheosis, Scrawl, and Panache regularly become some of the strongest picks during a run.

Other colorless cards still have their place depending on the deck you are building. Understanding which ones consistently provide value makes choosing rewards much easier during a run.