Slay the Spire 2 Best Relics Tier List: Strongest Picks

Relics are one of the biggest power spikes in Slay the Spire 2. Cards determine your strategy, but relics determine how smoothly that strategy actually works. Some relics improve every single fight, while others only shine in specific builds.

This tier list ranks the best relics in Slay the Spire 2 based on consistency, power across multiple characters, and how much they help stabilize difficult runs.

Slay The Spire 2 Best Relics Tier List

S Tier Relics

These relics are among the strongest in the game. They improve almost every deck and often define the direction of your run.

Ice Cream | Unspent energy carries over between turns which allows massive combo turns and removes wasted energy completely.
Gambling Chip | Discard any number of cards from your starting hand and redraw them which fixes bad opening hands.
Mummified Hand | Playing a Power makes another card in your hand free which enables extremely powerful turns in scaling decks.
Bag of Preparation | Draw two additional cards on the first turn which greatly improves early combat consistency.
Kunai | After playing three attacks in a turn gain Dexterity which scales defense extremely well in aggressive decks.
Shuriken | After playing three attacks in a turn gain Strength which dramatically increases damage output.

A Tier Relics

These relics are very strong and consistently improve most runs.

Tungsten Rod | Reduce all HP loss by one which blocks chip damage from burns, thorns, and multi hit attacks.
Lantern | Gain one extra energy on the first turn which helps stabilize difficult elite fights.
Ornamental Fan | Gain Block after playing three attacks which provides free defense for aggressive decks.
Pen Nib | Every tenth attack deals double damage which creates strong burst damage turns.
Pocketwatch | If you play three or fewer cards in a turn draw three additional cards next turn which rewards slower control decks.

B Tier Relics

These relics provide steady value but usually do not define a run on their own.

Oddly Smooth Stone | Gain one Dexterity permanently which improves every block card in your deck.
Vajra | Gain one Strength permanently which scales well with multi hit attacks.
Anchor | Start each combat with ten Block which protects you from early damage.
Thread and Needle | Start combat with Plated Armor which provides passive Block each turn.
Gremlin Horn | Whenever an enemy dies gain energy and draw a card which helps in multi enemy fights.

C Tier Relics

These relics are situational and usually weaker than other options.

Tiny House | Provides several small bonuses but none of them are strong enough to significantly impact a run.
Girya | Gain Strength by spending rest sites which slows down card upgrades and scaling.
Blood Vial | Heal a small amount at the start of combat which becomes less useful later in the run.

D Tier Relics

These relics often hurt your run unless you have a very specific strategy.

Glass Cannon | Doubles incoming damage which becomes extremely dangerous in later acts.
Greed’s Purse | Generates gold but costs energy which slows your deck in combat.

Character Relics That Become Much Stronger

Some relics become extremely powerful when paired with specific characters.

Ironclad

Red Skull | Gain Strength when below half health which works well with Ironclad aggressive playstyle.
Self Forming Clay | Gain Block whenever you lose HP which synergizes with self damage cards.

Silent

Snecko Skull | Apply additional Poison whenever Poison is applied which dramatically increases poison damage.
Tingsha | Deal damage when discarding cards which works well in discard focused decks.

Defect

Data Disk | Start combat with additional Focus which boosts Orb damage and defense.
Emotion Chip | Trigger passive Orb effects when taking damage which increases Orb value.

Regent

Lunar Pastry | Generates Stars each turn which supports Regent scaling mechanics.
Mini Regent | Gain Strength the first time you spend Stars each turn.

Necrobinder

Bone Flute | Gain Block when Osty attacks which strengthens summon builds.
Funerary Mask | Adds Souls into your draw pile which improves sacrifice strategies.

Final Blurb

Relics are one of the most important systems in Slay the Spire 2. The strongest relics improve consistency, scaling, and survivability across long runs.

Pay attention to how relics interact with your character and deck. A relic that looks average on its own can become incredibly powerful when paired with the right build.

FAQ

What are the best relics in Slay the Spire 2

Some of the strongest relics include Ice Cream, Gambling Chip, Mummified Hand, Bag of Preparation, Kunai, and Shuriken because they consistently improve most decks.