Mewgenics Best Classes Tier List: Strongest Picks Ranked And How To Unlock Them

The best classes in Mewgenics right now are Cleric, Fighter, and Mage. They give you the most control, the most carry power, and the most consistent runs. A few other classes deserve to move up or down compared to the usual rankings, especially once you factor in real campaign pacing and not just perfect drafts.

This list assumes solid skill rolls and normal progression through the Acts. RNG still matters, but some classes simply give you better odds.

S Tier Run Carriers

Cleric

Unlock by clearing Act 1 Alley

Cleric is still the safest and strongest class overall. Revive, injury removal, and strong healing keep your party alive deep into late zones. Open Wounds also lets Cleric deal serious damage when targets are low.

Late game fights hit hard. Cleric fixes mistakes and lets aggressive comps survive.

Fighter

Available by default

Fighter controls action economy better than most classes. Confront, Leap, and Meteor Slam close gaps fast. Spin, Side Slash, and Stoopzerk stack pressure quickly.

It does not need perfect items to function. It just works.

Mage

Available by default

Mage belongs in S tier. Magic Missile gives free chip damage, while Meteor Storm and Mega Blast wipe groups. INT and CHA scaling help maintain mana.

Line of sight can slow you down, but smart positioning solves most problems.

A Tier Strong And Flexible Picks

Hunter

Available by default

Hunter hits extremely hard with Heavy Shot and Arrow Flurry. With items like Monocle or Bullseye, missed shots stop being a real issue.

It drops slightly because it relies more on gear than Fighter or Mage. Still deadly with the right setup.

Butcher

Unlock by clearing Act 2 Core

Butcher deserves high placement. Meat Hook pulls enemies into Cleave range, and food drops sustain fights. High CON lets it stay in the front line.

Lower SPD limits mobility, but once it gets rolling, it controls close quarters fights well.

Thief

Unlock by clearing Act 1 Sewers

Thief moves up compared to most lists. +4 SPD is massive. Assassinate deletes targets when positioned correctly.

It is fragile, but strong movement and teleport skills fix that. Played well, it feels like a scalpel.

Psychic

Unlock by clearing Act 2 Moon

Psychic wins fights through control. Gravity Pull and Increase Gravity can slow or bunch enemies together for knockback damage.

It does not top damage charts, but it makes the entire team better.

B Tier Good But Draft Dependent

Tank

Available by default

Tank absorbs damage with Steelskin and protects allies with Goad and Bodyguard. It does its job well.

It drops slightly because pure defense is slower than strong offense or control. You win, just not as fast.

Monk

Unlock by clearing Act 3 Labs

Monk has two basic attacks and stance switching, which sounds great. The issue is scaling, since -1 STR and -1 DEX lower damage output.

With the right martial arts skills, it spikes hard. Without them, it feels awkward.

Necromancer

Unlock by clearing Act 1 Boneyard

Necromancer can high roll with Soul Link and strong reanimations. Revived enemies can swing entire fights.

Without key skills, though, it becomes setup heavy and slower than other DPS options.

C Tier Inconsistent Or RNG Heavy

Druid

Unlock by clearing Act 2 Crater

Druid can summon, heal, and shapeshift. The crow companion helps early.

Random starting skills and lower CON make it unreliable. Some runs feel smooth, others feel mismatched.

Tinkerer

Unlock by clearing Act 2 Bunker

Tinkerer crafting can create powerful weapons. Starting battles with strong crafted gear feels great.

The problem is consistency. Without Tech and Duct Tape, it depends too much on luck.

D Tier Only In Specific Situations

Collarless

Available by default if no collar is chosen

Collarless relies on generalist buffs and coin skills like teleport and healing. It lacks strong scaling compared to real classes.

It works if the cat already has strong innate skills. Otherwise, it struggles to carry.

Special Case Tier

Jester

Unlock late in Act 3

Jester pulls abilities from every class pool. You might get Meteor Slam early, or you might not.

It can be incredible or underwhelming. It does not fit neatly into normal tiers because it depends entirely on what it rolls.

Final Blurb

Cleric, Fighter, and Mage remain the most consistent top picks in Mewgenics. Hunter, Thief, and Psychic all perform better than most people rank them once you understand positioning and item synergy. Tank drops slightly because defense alone does not close fights quickly.

Drafts and gear still matter, but if you want smoother runs with fewer resets, lean into S and high A tier options and build around their strengths.