Mewgenics Lost Quest Item Guide: Do You Lose Them Forever
If you lose a run while carrying a quest item in Mewgenics, the item is not permanently gone from your save file. Main quest items return on a new run, and side quest items go back into the quest pool. You are not locked out of progression.
The system is harsher than normal loot, but it is not permanent punishment.
What Happens If You Lose A Main Quest Item
Main quest items like Throbbing Gristle or the Meat Cube are tied to in-game progress.
If your run ends while carrying one, it will reappear when you start a new run. Sometimes it shows up immediately in the next expedition prep screen.
It may not appear in the first equipment menu if you did not bring it, but it still exists in your quest inventory back at the House.
You cannot permanently brick your save by failing one of these.
What Happens If You Lose A Side Quest Item
Side quest items work differently.
If you fail the run, the item itself is gone for that run, but the quest goes back into the Beanies quest pool. It can be rolled again later when you donate more cats.
There is no instant retry option. You simply have to wait for it to reappear.
Why It Feels Like It Is Gone
There are a few reasons players think the item vanished forever.
If the carrier cat dies mid run, the item is destroyed for that attempt. That is intended.
If you start a new run and do not equip it, it may not appear in your active inventory after the first combat. Quest items are managed separately from normal depot gear.
Sometimes the item only visibly reappears when starting a fresh expedition.
It can look gone, but it is not deleted from your save.
Important Rule About Carrier Death
If the cat holding the quest item dies during the run, the quest fails for that run.
For example, with Meat Cube or Throbbing Gristle, if the carrier drops, the item is destroyed for that expedition. You must start a new run and try again.
This does not remove the quest permanently. It just resets your attempt.
Can You Miss Quests Permanently
No.
Main quest items return on new runs. Beanies side quests re enter the random pool if failed.
There is no permanent lockout mechanic tied to losing a single attempt.
Final Blurb
Losing a quest item during a run hurts, but it does not brick your file. Main quest items come back on new expeditions, and side quests cycle back into the pool.
Failing a run means retrying later, not starting over from scratch. Just be more prepared next time you carry it out.
FAQ
Did I permanently lose my quest item?
No. It returns on a new run or reenters the quest pool.
Why didn’t I see it after the first combat?
Quest items are handled separately from normal gear and may not appear in the initial equipment screen.
If my carrier cat dies, is the quest gone forever?
No. It only fails for that run.
How do I retry a side quest?
Donate more cats to Beanies and wait for the quest to reappear in the pool.
