Resident Evil Requiem: How to Destroy Padlock
To destroy the padlock in Resident Evil Requiem, you must find Corrosive and use it on the locked sun puzzle box in the Lead Researcher’s Office. The padlock cannot be shot or broken manually. Once you have Corrosive, interact with the lock and Grace will pour it on, dissolving it instantly.
This step is required to obtain the second quartz in the clinic section.
Where To Get Corrosive In The Clinic
After reading the document in the Lead Researcher’s Office that mentions Corrosive, leave the room and prepare for trouble. A large baby creature will begin chasing you shortly after.
Before fully retreating, grab the Level 1 Access Wristband from the body nearby. Then move downstairs and create distance until it is safe to circle back through the East Wing.
The Corrosive is located in the Conference Room area.
To reach it:
Head to the Conference Room on the lower level
Clear the zombies inside, including a Screamer variant
Enter the back room connected to the Conference Room
Pick up the Corrosive from the counter
Once collected, it appears in your inventory as a usable key item.
How To Destroy The Padlock
Return to the Lead Researcher’s Office after securing the Corrosive. You may encounter Victor during this return, so be ready.
Approach the locked sun puzzle box and interact with the padlock. Grace will automatically use the Corrosive, melting the lock and unlocking the puzzle mechanism.
You do not need to combine the item manually. The interaction prompt handles it.
Solving The Sun Puzzle Box
After dissolving the padlock, you must solve the symbol sequence on the box.
Check the photograph on the desk in the same office. The image shows the correct symbol order partially visible.
The correct combination from left to right is:
Star
Sun
Moon
Sun
Confirm the sequence to open the box.
Inside, you will find the second quartz along with a research book tied to the organ box instructions.
What The Padlock Unlocks
Destroying the padlock gives access to the sun puzzle box, which contains:
The second quartz
A key document for future progression
The quartz is required to unlock the courtyard door in the clinic’s central area.
Without dissolving the padlock, you cannot continue this portion of the main objective.
Final Blurb
The padlock in the Lead Researcher’s Office is one of those classic Resident Evil progression gates. If you do not have Corrosive, it is not opening. Grab the Corrosive from the Conference Room, survive the baby chase, melt the lock, and solve the symbol sequence. Clean, direct progression. No wasted ammo trying to shoot it open.
FAQ
How do you destroy the padlock in Resident Evil Requiem
You must use Corrosive on the locked sun puzzle box in the Lead Researcher’s Office.
Where is Corrosive located in the clinic
Corrosive is found in the back room connected to the Conference Room in the East Wing.
Can you shoot the padlock off
No, the padlock can only be removed using Corrosive.
What is the sun puzzle box solution
The correct symbol order is Star, Sun, Moon, Sun from left to right.

